Cerezyme® (imiglucerase)

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Gaucher disease is an inherited genetic condition that causes fatty deposits to build up in certain organs and bones. People with Gaucher disease do not have enough of the enzyme glucocerebrosidase that helps the body to break down a certain type of fat molecule, glucocerebroside. As a result, cells fill up with the undigested fat. These cells are referred to as Gaucher cells. Learn more about our Gaucher disease therapy management.

The course of the disease is quite variable. The most common symptoms of Gaucher disease are enlargement of the liver and spleen, anemia, reduced platelets (resulting in easy bruising and long clotting times), bone pain, bone infarctions often leading to damage to the shoulder or hip joints, and a generalized demineralization of the bones (osteoporosis). The weakening of the bones can then lead to spontaneous fractures.

Accredo has been working with lysosomal storage disorder (LSD) therapies since 1991 and has gained extensive experience that serves as a valuable resource to our patients.

Referrals

Other Resources:

Cerezyme.com

Genzyme Corporation

National Gaucher Foundation

NORD - National Organization for Rare Diseases